Inclusion in the latest version of the WHO Guidelines for malaria is a key step towards broader use of the medicine
GENEVA, Switzerland, November 25, 2022/APO Group/ —
MMV (http://www.MMV.org) and Shin Poong Pharm. Co., Ltd. welcome the formal inclusion of Pyramax® (pyronaridine-artesunate) in the World Health Organization’s (WHO) Guidelines for Malaria (http://bit.ly/3EZSJep) following an extensive review process.
The WHO’s Guidelines for the Treatment of Malaria are the standard reference which guide country-level policies for managing malaria. New medicines are only recommended for inclusion following a robust and in-depth evaluation of evidence using the GRADE (http://bit.ly/3XuGnSy) framework, which provides a systematic approach for making clinical practice recommendations. Following this review – which included one of the largest clinical studies to evaluate real-world efficacy and safety of any antimalarial – the Guideline Development Committee recommended the formal inclusion of Pyramax in the guidelines with a “STRONG” recommendation – the highest level of confidence.
Pyramax is a fixed dose artemisinin-based combination therapy (ACT) and the only one to be specifically indicated for the blood-stage treatment of the two dominant species of malaria parasite: P. falciparum and P. vivax. The medicine is also available in a child-friendly granule formulation to ensure palatability and therefore correct dosage in this vulnerable population.
Both Pyramax tablets and Pyramax granules received European Medicines Agency (EMA) positive scientific opinions from the Committee for Medicinal Products for Human Use (CHMP) through Article 58, based on a robust development programme. To date, over 2.9 million malaria patients have been treated with the medicine, including children under the age of 1.
Both formulations are currently registered for the treatment of uncomplicated malaria in 29 countries in Africa and Asia.
Following the positive scientific opinions for use, a large Cohort Event Monitoring study was implemented in 5 African countries [1] under the supervision of the CANTAM Network [2] to evaluate the safety and effectiveness of Pyramax under conditions similar to everyday clinical practice. This study, which reported high effectiveness (D28 PCR-adjusted cure rate of 98.6%), included over 8,500 acute malaria episodes in 7,154 patients, and has recently been published in PLoS Medicine [3].
Pyramax was included in the WHO’s list of pre-qualified medicines in 2012, and in the WHO’s Essential Medicines Lists for both adults and children in 2017. Pyramax has subsequently undergone a positive review by the WHO’s Advisory Committee on the Safety of Medicinal Products in 2019, which included a review of interim data from the CANTAM study.
The addition of Pyramax to the WHO Guidelines for malaria is an achievement that we are proud to have reached with our long-standing partner Shin Poong Pharm. Co., Ltd.
Following this review in October 2019 and pending the next revision of their Guidelines for Malaria, the WHO published an Information Note supporting the use of Pyramax at country level, stating that “artesunate-pyronaridine can be considered a safe and efficacious ACT for the treatment of uncomplicated malaria in adults and children weighing 5 kg and over in all malaria-endemic areas….countries can consider including this medicine in their national treatment guidelines for the treatment of malaria”.
“The addition of Pyramax to the WHO Guidelines for malaria is an achievement that we are proud to have reached with our long-standing partner Shin Poong Pharm. Co., Ltd.,” said Dr David Reddy, MMV’s CEO. “We ventured into the Pyramax project to help save the lives of adults and children with malaria. Therefore, we will continue to work with Shin Poong to register both the tablets and granules of Pyramax in more malaria-endemic countries, facilitating equitable access to this important new addition to the malaria treatment toolkit.”
“The official inclusion of Pyramax into WHO’s Guidelines for malaria is a crucial step allowing malaria endemic countries to choose Pyramax as a first line ACT with confidence. The managerial decision to commence the Pyramax project was based on Shin Poong’s core values and company policies, which have guided us for over half a century. We will continue to produce qualified products to supply potent, reliable, simple treatment to patients”, said Shin Poong Pharm. Co., Ltd.
[1] Gabon: Albert Schweitzer Hospital (CERMEL), Lambaréné, Côte d’Ivoire: Health Center of Azaguié & Health Center of Agboville, Cameroon: Biotechnology Center, University of Yaoundé & Mfou District Hospital, Congo: Congo foundation for the Medical Research, Brazzaville, Makélélé Hospital, Health Center of Madibou, DR of Congo: Faculty of Medicine, University of Kinshasa, Mont-Amba Hospital, Kinshasa, Evangelic Medical Institute of Kimpesé
As an African-owned investment banking and advisory firm, Premier Invest is aiming to bridge Africa’s oil and gas financing gap through strategic partnerships in the sector
LONDON, The United Kingdom, July 12, 2024/APO Group/ —
Rene Awambeng, Managing Partner at investment banking and advisory firm Premier Invest, outlined Africa’s current oil and gas financing gap and strategies for unlocking global capital at the Invest in African Energy reception -organized by the African Energy Chamber (www.EnergyChamber.org) – in London on Thursday. Last month, Premier Invest signed a milestone agreement with Shell to enable access to financing for oil and gas projects across the continent.
The agreement to co-finance and originate oil and gas agreements in Africa aims to drive growth in the oil and gas sector across the continent
Under the strategic partnership, the two companies will collaborate to identify and co-finance oil and gas transactions in Africa that have the potential to generate significant returns, while creating value for local communities and economies.
“The agreement to co-finance and originate oil and gas agreements in Africa aims to drive growth in the oil and gas sector across the continent. We will work together to identify and evaluate potential opportunities in the oil and gas market and leverage our respective expertise to fund projects that have the potential for significant returns. This is a significant step forward in our commitment to support the growth of the sector,” said Awambeng.
The partnership serves to address the persistent lack of FDI on the continent – in which Africa receives only five percent of global investment – placing African countries at a disadvantage when it comes to establishing requisite infrastructure to produce refined petroleum products and increase power generation and distribution capacities. According to Awambeng, 50% of oil product consumption in Africa is met through imports, despite Africa being a net crude oil producer.
“To address these finance challenges, we have put together an African-owned and managed investment banking firm to offer a range of financial advisory services supporting clients across industry to invest in small, medium and large-sized projects… The continent lacks funds to finance its oil and gas projects, as well as needs technology to manage its oil and gas industry,” said Awambeng.
Distributed by APO Group on behalf of African Energy Chamber
AOG 2024 serves as Angola’s premier energy event, providing unparalleled opportunities for international investors and stakeholders to gain access to the oil and gas market
LUANDA, Angola, July 12, 2024/APO Group/ —
Angola’s oil and gas industry is growing rapidly, with a $60 billion investment pipeline planned for the next five years, a 2025 limited tender on the cards and industry reforms offering improved fiscal and contractual terms. The county’s premier industry event Angola Oil & Gas (AOG) connects international stakeholders to the market, serving as a bridge between foreign players and Angolan projects.
AOG is the largest oil and gas event in Angola. Taking place with the full support of the Ministry of Mineral Resources, Oil and Gas; national oil company Sonangol; the National Oil, Gas and Biofuels Agency; the African Energy Chamber; and the Petroleum Derivatives Regulatory Institute, the event is a platform to sign deals and advance Angola’s oil and gas industry. To sponsor or participate as a delegate, please contact sales@energycapitalpower.com.
Strong International Focus
In recent months, Angola has been strengthening cooperation with various global partners to support oil and gas development. Recent deals include with Italy, the UAE, South Korea, Ivory Coast and many more. These deals and future collaborations are expected to drive project development and innovation in Angola while supporting global demand through Angolan exports.
The 2024 edition of the conference builds on this to bring new players to the market while promoting projects, partnerships and potential investment opportunities. In addition to local and regional delegates, AOG 2024 will feature the participation of delegations from China, the UK, the UAE, Germany, Portugal, Brazil and many more. International companies are invited to participate in the event and seize new opportunities in Angolan oil and gas.
Access Upcoming Projects
Last month, Angola’s national concessionaire for the oil and gas industry the National Oil, Gas & Biofuels Agency (ANPG) announced a series of measures that aim to support crude oil production in Angola. This comes as the country recently awarded oil and gas companies Etu Energias, Effimax Energy and Grupo Simples Oil a new concession for Block CON 8, stipulating an exploration phase lasting five years from the signing of the contract.
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Angola is enhancing cooperation with global players, including IOCs such as Chevron, TotalEnergies, Azule Energy and ExxonMobil, to bring new projects online and maintain hydrocarbon production above 1.1 million barrels per day through 2027. A key component of AOG 2024 is unparalleled access to upcoming projects. Attendees will be given exclusive access to the latest requests for proposals, tenders, market trends, policies and regulations shaping the sector.
https://apo-opa.co/3zFEZVZ
Drive Real Investment
Each year, AOG cements itself as the platform of choice for partnerships, collaborations and multi-billion-dollar deal signings. In 2023, seven industry-advancing deals were signed, laying the foundation for collaboration, market growth and future prosperity. In 2024, this trend is expected to continue as foreign companies travel to Luanda to engage with Angolan companies. The conference’s multi-track program covers the entire oil and gas value chain, providing insight into investment opportunities and strategic projects.
Participate in Exclusive Networking
The AOG 2024 conference serves as an opportunity for local, regional and international delegates to collaborate and discover new avenues for investment. Delegates can connect with top energy investors and executives – from operators, IOCs, NOCs and independents – as well as government officials, industry innovators and financiers to expand their professional network.
The event offers extensive opportunities to network and build meaningful business relationships, including exclusive networking breaks and lunches, the closing Networking Cocktail as well as the Gala Dinner and Awards which recognizes the companies pioneering the oil and gas industry in Angola.
Help Fuel Development
With the recent commencement of construction at Angola’s first integrated economic zone as well as its first aluminum industrial park, the country is on track to accelerate economic diversification and sustainable development. Apart from oil and gas, AOG 2024 is poised to set the benchmark for development in Angola while facilitating a strategic investment hub for various sectors in the country’s public and private sectors.
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Angola continues to provide great opportunities for international investors to develop energy projects that serve local and international energy demand. AOG 2024 targets key initiatives in the country including a heightened exploration drive, gas monetization, local content development and renewable energy and will clearly show Angola’s ambition and future plans for development.
Distributed by APO Group on behalf of Energy Capital & Power.
Ahead of a new licensing round, Liberia is offering incentives for early investors, coupled with extensive 2D and 3D seismic data in its Liberia and Harper basins and a working petroleum system previously established by global majors
CAPE TOWN, South Africa, July 12, 2024/APO Group/ —
Kicking off the Invest in African Energy (IAE) reception in London on Thursday, Marilyn Logan, Director General of the Liberia Petroleum Regulatory Authority (LPRA), showcased Liberia’s available oil and gas blocks and upstream investment opportunities. The reception served to connect major technical and financial partners to Africa’s energy sector ahead of the African Energy Week: Invest in African Energy conference in Cape Town this November, organized by the African Energy Chamber (AEC) (www.EnergyChamber.org).
Global investors have been clamoring to Africa’s frontier markets in recent months, with countries like Namibia, Mauritania and Mozambique attracting sizable oil and gas CapEx spending, coupled with a renewed exploration focus in West Africa. Liberia represents a proven petroleum system supported by extensive reprocessed 2D and 3D multi-client seismic data in its Liberia and Harper basins.
“Liberia stands out as a new and exciting destination for oil and gas exploration. Positioned strategically on the West Africa Transform Margin, Liberia shares geological similarities with the Jubilee field in Ghana and [discoveries] in Guyana. We are on the verge of a new decade realizing untapped potential in West Africa, and Liberia is ready to play a pivotal role.”
Our round is expected to attract serious investors, with Liberia offering incentives for early investment and ensuring the yield of substantial returns
“Many years ago, many thought Namibia was an oil man’s graveyard…Today, there are even more prospects in countries like Liberia. The belief coming out of [London] drove exploration in places like Namibia – Liberia could be a replica of that,” added NJ Ayuk, Executive Chairman of the AEC.
Logan highlighted the role of majors ExxonMobil and Chevron in confirming the presence of a working hydrocarbon system, which has been supported by recent seismic surveys and data reprocessing that show promise of significant reserves. In 2021, the country opened a direct negotiation process for 33 offshore blocks in the Harper and Liberia basins, with plans to launch a new round later this year.
“Liberia’s upcoming 2024 licensing round provides the opportunity to secure prime exploration blocks. Our round is expected to attract serious investors, with Liberia offering incentives for early investment and ensuring the yield of substantial returns,” said Logan.
In addition to its prospective hydrocarbon resources, Liberia offers a competitive fiscal regime, stable governance and a conducive operating environment. According to Logan, the country has established a fee structure that incentivizes and rewards oil and gas investors with appropriate returns, while still ensuring Liberia retains social and economic benefits from oil and gas extraction activities.
“On the policy side, the Liberian government has implemented a robust oil and gas program to ensure a conducive environment for oil and gas investments, including a streamlined regulatory process and stable and democratic political environment,” she said.
“We have to keep an enabling environment – when we enable you to put in money and finance projects, then we both win. The idea of resource nationalism has to go, and also the demonization of the energy industry,” stated Ayuk.
Distributed by APO Group on behalf of African Energy Chamber.
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